Olle Melander Selected Research

Diltiazem (Cardizem)

10/2018	IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem (NORDIL) study and the Integrated Imaging and Biomarker Study 3 (IBIS-3).
6/2015	TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
8/2013	Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.
7/2013	Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes.
2/2011	A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients.
4/2009	The myocardial infarction associated CDKN2A/CDKN2B locus on chromosome 9p21 is associated with stroke independently of coronary events in patients with hypertension.
7/2008	Interaction between renal function and microalbuminuria for cardiovascular risk in hypertension: the nordic diltiazem study.

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Olle Melander Research Topics

Disease

71	Neoplasms (Cancer) 08/2022 - 11/2005
64	Hypertension (High Blood Pressure) 01/2022 - 05/2002
64	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 08/2004
33	Type 2 Diabetes Mellitus (MODY) 11/2021 - 05/2002
31	Obesity 01/2022 - 06/2007
26	Coronary Artery Disease (Coronary Atherosclerosis) 12/2021 - 01/2008
24	Insulin Resistance 01/2022 - 01/2009
21	Diabetes Mellitus 12/2021 - 01/2007
21	Stroke (Strokes) 01/2021 - 07/2009
20	Atherosclerosis 01/2021 - 08/2009
19	Myocardial Infarction 04/2019 - 12/2006
18	Ischemic Stroke 11/2021 - 05/2011
17	Heart Failure 01/2022 - 10/2009
17	Orthostatic Hypotension (Postural Hypotension) 10/2020 - 05/2009
14	Atrial Fibrillation 01/2022 - 11/2010
13	Inflammation (Inflammations) 01/2022 - 06/2011
11	Lung Neoplasms (Lung Cancer) 03/2022 - 06/2016
11	Coronary Disease (Coronary Heart Disease) 12/2021 - 03/2010
11	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 08/2006
9	Breast Neoplasms (Breast Cancer) 02/2022 - 10/2012
8	Sepsis (Septicemia) 01/2022 - 08/2013
8	Chronic Renal Insufficiency 10/2021 - 05/2010
8	Essential Hypertension 06/2015 - 03/2004
7	Dyspnea (Shortness of Breath) 01/2022 - 10/2015
7	Dyslipidemias (Dyslipidemia) 01/2022 - 05/2012
7	Genetic Risk Score 01/2021 - 07/2013
6	Vasovagal Syncope 12/2019 - 09/2010
6	Syncope (Fainting) 12/2019 - 08/2015
5	Prostatic Neoplasms (Prostate Cancer) 04/2022 - 06/2016
5	Non-alcoholic Fatty Liver Disease 11/2021 - 05/2012
5	Abdominal Aortic Aneurysm 01/2021 - 01/2017
5	Postural Orthostatic Tachycardia Syndrome 01/2021 - 01/2017
5	Abdominal Obesity 01/2017 - 07/2011
4	Overweight 10/2021 - 01/2009
4	Peripheral Arterial Disease 07/2021 - 01/2008
4	Atherosclerotic Plaque (Atheroma) 01/2019 - 01/2016
3	Venous Thromboembolism 08/2022 - 03/2016
3	Septic Shock (Toxic Shock Syndrome) 01/2022 - 01/2016
3	Critical Illness (Critically Ill) 01/2022 - 01/2019
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 11/2018
3	Hyperglycemia 11/2021 - 05/2015
3	Infections 11/2021 - 07/2017

Drug/Important Bio-Agent (IBA)

57	Biomarkers (Surrogate Marker)IBA 03/2022 - 11/2010
35	LipidsIBA 02/2022 - 01/2007
24	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2010
22	Triglycerides (Triacylglycerol)IBA 12/2021 - 06/2007
21	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 11/2005
20	HDL CholesterolIBA 01/2021 - 02/2008
19	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 06/2007
17	LDL CholesterolIBA 01/2021 - 02/2008
16	CholesterolIBA 01/2022 - 01/2008
16	Vasopressins (Vasopressin)IBA 12/2021 - 04/2015
15	oxidized low density lipoproteinIBA 01/2022 - 02/2008
14	Insulin (Novolin)FDA Link 11/2018 - 08/2009
13	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2021 - 08/2004
13	Natriuretic PeptidesIBA 09/2019 - 03/2009
12	C-Reactive ProteinIBA 01/2021 - 01/2007
12	Atrial Natriuretic Factor (ANF)IBA 01/2021 - 05/2002
12	SaltsIBA 01/2019 - 05/2002
11	AdrenomedullinIBA 03/2022 - 11/2010
11	Peptides (Polypeptides)IBA 01/2022 - 03/2012
10	NeurotensinIBA 01/2022 - 10/2012
10	Biological ProductsIBA 04/2021 - 01/2007
10	hydroxide ionIBA 10/2020 - 01/2010
9	Cystatin CIBA 01/2021 - 07/2009
8	proadrenomedullinIBA 01/2021 - 07/2009
8	P-2 (P 2)IBA 10/2019 - 03/2009
8	Pharmaceutical PreparationsIBA 01/2019 - 05/2010
7	Hormones (Hormone)IBA 11/2020 - 01/2012
7	Lipoproteins (Lipoprotein)IBA 01/2020 - 07/2009
7	Arginine Vasopressin (Argipressin)IBA 12/2019 - 01/2009
7	LDL Lipoproteins (beta Lipoproteins)IBA 01/2019 - 02/2008
7	Diltiazem (Cardizem)FDA LinkGeneric 10/2018 - 07/2008
6	Apolipoproteins B (ApoB)IBA 02/2022 - 06/2016
6	ApolipoproteinsIBA 02/2022 - 05/2012
6	EnzymesIBA 01/2022 - 07/2012
6	Amino Acids FDA Link 10/2021 - 05/2012
6	DNA (Deoxyribonucleic Acid)IBA 10/2021 - 01/2007
6	proneurotensinIBA 01/2021 - 10/2012
5	Apolipoprotein A-I (Apolipoprotein A1)IBA 02/2022 - 06/2016
5	Blood Proteins (Serum Proteins)IBA 03/2021 - 10/2015
5	ORALIT (ORS)IBA 11/2020 - 07/2012
5	pro-brain natriuretic peptide (1-76)IBA 01/2020 - 08/2004
5	HDL LipoproteinsIBA 01/2019 - 02/2008
5	DiureticsIBA 01/2018 - 04/2009
4	CreatinineIBA 12/2021 - 12/2015
4	Growth Differentiation Factor 15IBA 10/2021 - 03/2016
4	1-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA 01/2021 - 01/2017
4	Growth Hormone (Somatotropin)IBA 01/2021 - 10/2014
4	Glutamic Acid (Glutamate)FDA Link 01/2018 - 03/2004
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018 - 03/2010
4	Urokinase Plasminogen Activator ReceptorsIBA 03/2017 - 01/2014
4	AdiponectinIBA 01/2017 - 11/2011
3	Immunoglobulin G (IgG)IBA 01/2022 - 07/2017
3	Immunoglobulin M (IgM)IBA 01/2022 - 01/2018
3	Fatty Acids (Saturated Fatty Acids)IBA 12/2021 - 01/2016
3	AntibodiesIBA 12/2021 - 01/2018
3	Phenylalanine (L-Phenylalanine)FDA Link 10/2021 - 01/2016
3	Caspase 3 (Caspase-3)IBA 10/2021 - 01/2017

Therapy/Procedure

16	Therapeutics 01/2021 - 01/2007